Features

Flexible lattices in 2D and 3D, voxel-based shape editing, scripted shape designers, 3D object importer, strand editors, and more.

Features »

Example files

Try the software with some of the structures we implemented in our paper.

Example files »

Contact

We'd love to hear from you!

Contact »

Here's a sampling of available features:

Nanostructure shape design

• Full-featured, graphical system editor to design structures using a 3D interface.
• Built-in scripting modules can be implemented to automate feature designs

Strand design and editing

• Automatic generation of strand routing based on voxel design and lattice selection - easy to build discrete 2D, 3D, and periodic DNA brick structures.
• In situ manipulation of strands on a 3D interface, including deleting, adding, extending, and ligating strands

Sequence design

• Random sequences can be automatically generated and exported to a CSV file for ordering.
• Existing sets of sequences can be loaded into the structure for strand reuse.

Importing/exporting

• Capable of importing a wide range of file types including 3D rendered OBJ, caDNAno strand diagrams, and CSV files for sequences
• Designs can be exported on the voxel, strand, and sequence level to a variety of formats including caDNAno, CanDo, and OBJ

Interface

• Fully integrated design workflow with multiple perspectives and selectable views.
• Customizable and scriptable interface lets you automate repetitive tasks

Screenshots

Instructions for viewing Strand diagrams in Nanobricks

We provide a number of files that can be viewed using Nanobricks, caDNAno, or both. Links and descriptions of the file contents can be found in the table below. 

caDNAno schematics

To view the caDNAno schematics, use the legacy version of caDNAnoSq. Note that the large size of these files will make visualizing the 2D layout very slow. Alternatively, the caDNAno files can be imported into Nanobricks.

To import the files, first set the canvas to be larger than that the size of the structure. For the case of the shapes, one could use 50x50x50 voxel canvas using the 13-nt rectangular lattice.

Following to visualize the correct orientation of strands, one would press the “SHIFT” key to flip the structure along the X axis during importation. This reflection is necessary because the 0,0 position is in the opposite corner in the Nanobricks file compared to in the caDNAno file.

Nanobricks Schematics

Voxelized designs of the 3D shapes can be opened directly in the Nanobricks software.

Structure descriptions