Programming DNA Tube Circumferences

Peng Yin, Rizal F. Hariadi, Sudheer Sahu, Harry M.T. Choi, Sung Ha Park, Thomas H. LaBean , John Reif

Science, 321:824-826, 2008

Downloads: PDF, 3 pages.

Abstract: Synthesizing molecular tubes with monodisperse, programmable circumferences is an important goal shared by nanotechnology, materials science, and supermolecular chemistry. We program molecular tube circumferences by specifying the complementarity relationships between modular domains in a 42-base single-stranded DNA motif. Single-step annealing results in the self-assembly of long tubes displaying monodisperse circumferences of 4, 5, 6, 7, 8, 10, or 20 DNA helices.

Supplementary material:PDF, 26 pages


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